Endocrine Abstracts

Introduction: Secondary failure (SF) to treatment with oral therapy is defined as the absence of a favorable reaction to the oral therapy which was effective in the previous course of the treatment. The aim of the work was to investigate the acute effects of the short-term insulin therapy on the secretory ability of endocrine pancreatic beta cells and the insulin resistance. Materials and Methods: 98 patients with diabetes mellitus type 2 (DM T2) and confirmed the SF to the or...

Introduction: Clinical assessment of atherosclerotic complications in type 2 diabetes mellitus (DM) was diverted to the detection of subclinical form of atherosclerosis using the non-invasive diagnostic methods. Surrogate markers of subclinical atherosclerosis are carotid intima-media thickness (IMT) and albuminuria. The aim of this study was to analyze a relationship between the presence of albuminuria and carotid IMT in patients with type 2 DM and silent ischemia.<p clas...

Introduction: The diagnostic criteria of polycystic ovary syndrome (PCOS) are still under discussion and the hormonal parameters, including anti-Mullerian hormone range and hyperandrogenism, are not determined. Serum AMH level has been proposed as a surrogate marker for PCOM and could, therefore, be integrated in the diagnostic classifications for PCOS\. The aim of the present study was to characterize hormonal features of PCOS and to establish the most important hormonal para...

Background: Low adiponectin levels in polycystic ovarian syndrome (PCOS) have been largely attributed to obesity which is common among these patients. In addition, evidence also suggests that low adiponectin in PCOS may be related to androgen excess in these women. Therefore, the aim of the present study was to examine the association of adiponectin levels and androgens in women with PCOS.Methods: A total of 60 women with PCOS who met the 2003 Rotterdam ...